New York county bans unvaccinated minors in public as measles spreads
Purdue Pharma to settle allegations it illegally marketed OxyContin
Connecticut US lawmakers react to Barr’s summary of Mueller report
Congo's Ebola epidemic exceeds 1,000 cases
Drinking Hot Beverages Like Tea Linked to Esophageal Cancer
Study sees immune therapy scoring big win against lung cancer
17 April 2018, 12:38 | Randall Craig
American Cancer Society via Getty Images
"It's pretty incredible times to have so many positive studies at once", added Matthew Hellmann, a lung cancer specialist at Memorial Sloan Kettering Cancer Center, who led one of the studies.
The combined use of standard chemotherapy with pembrolizumab was "superior in terms of response - keeping people alive without progression of their cancer - and improving the overall survival of patients with metastatic lung cancer compared to chemotherapy alone", said Gandhi. It's the principal form of lung cancer and found most commonly in people who have smoked. But Merck, the company that makes it, wanted to find out how the drug works in patients who aren't obvious candidates as determined by that blood test.
The new studies suggest that different types of tumors should receive different treatment regimens, all including immune therapy, Hellmann said.
He said the results established the double-immunotherapy combination as a first-line treatment for patients with a high tumor mutational burden, but that it was too early to know whether the treatment leads to longer survival. Serious side effects were a little more common in the chemo group. The most common issues in both groups were nausea, anemia and fatigue.
A study involving people with advanced stage lung cancer found it nearly doubled their survival time, while another revealed that immunotherapy treatment shrank tumours before surgery.
The odds of survival can greatly improve for people with the most common type of lung cancer if, along with the usual chemotherapy, they are also given a drug that activates the immune system, a major new study has shown. "This notion of 'cancer interception" has the potential to stop cancer in its tracks'.
Two thirds were given immunotherapy drugs combined with chemotherapy while...
Chief of Medical Oncology, Dr. Roy Herbst from the Yale Cancer Center said that, "I've been treating lung cancer for 25 years now, and I've never seen such a big paradigm shift as we're seeing with immunotherapy". "It's not a home run yet but it's a pretty good double".
Chemotherapy may no longer be the standard cancer treatment after the publication of a series of studies by the American Association for Cancer Research in Chicago. But it turns out to be a reasonable strategy.
Dr. H. Jack West, an often skeptical cancer specialist at the Swedish Cancer Institute in Seattle, saw the data presented at the meeting in Chicago and called them "huge results."
Immunotherapies are quickly increasing survival rates for some of the deadliest cancers in the world.
A course of treatment with Keytruda can cost $150,000, so an expanded market could mean billions of dollars in additional revenue. Those not given Keytruda were allowed to switch to it if their cancer worsened.
"We have a tool that helps us determine who are the patients that are most likely to benefit from this combination", Hellmann said. Researchers already had known that patients with high levels of the protein were more likely to respond to immunotherapy.
Dr. Matthew Hellmann of Memorial Sloan Kettering Cancer Center in NY led a study testing the Opdivo-Yervoy combo versus chemo in a slightly different group of newly diagnosed advanced lung cancer patients. Patients with those mutations (called EGFR and ALK) were not included in this study, and instead were referred to treatment with the drugs that target their mutation.
School Board Approves Administrative Moves
Buehrer said after reviewing the matter with the school district's legal counsel, he believed the bid should be awarded. High school officials contacted Rapacz, who worked with detectives to find and interview the student and his guardian.
Police arrest Las Cruces man accused of armed robbery
According to police, the victim allowed Gonzales to enter and was surprise when two other men appeared and also entered the house. Court documents say Antill went into the Nickel Ante Casino on Sherwood Street around 8:30 p.m. wearing a black ski mask.
Venezuelan woman sexually assaulted, robbed
Sexual assaults often go widely unreported, as victims don't wish to become part of a police investigation or court proceedings. The court observed that the girl has been consistent in her statements before the police and the court.
West Ham United 1-1 Stoke City
It looked as if it had paid off in some style when Hart spilled Xherdan Shaqiri's shot and Crouch turned home from close range. Then a low Edimilson Fernandes drive flew past Butland but Arnautovic, this time clearly offside, was in the keeper's way.
Night Court actor Harry Anderson found dead at 65
Our thoughts and condolences go out to Anderson's family, friends, and fans during what has to be an incredibly hard time. Asheville Police responded to the actor's home at 6:41 a.m., where he was found dead.
Judge Strikes Down Appeal For Alfie Evans' Life
Speaking outside the hospital, Alfie's dad declared "it's not over" while crowds of supporters chanted "get him out". Alfie Evans, born May 9, 2016, is lying critically ill in Alder Hey Children's NHS Foundation in Liverpool.