"He played the first half-hour (against Atletico), but he aggravated his injury, and the recovery time needed for that type of injury is three weeks", Deschamps said after revealing his squad live on television station TF1's evening news programme.
So too did Dimitri Payet, perhaps as a result of his limping out of Wednesday's UEFA Europa League final.
After returning from injury at the end of Manchester City's record-breaking Premier League title success, Benjamin Mendy has done enough to earn a place, although team-mate Aymeric Laporte - City's record signing - misses out.
Lacazette and Martial are both on a standby list of 11 players with United winger Martial having 18 caps and starting France's 3-1 friendly victory over Russian Federation in March.
Another player to miss out was Arsenaldefender Laurent Koscielny, who ruptured an Achilles tendon playing against Atletico in the Europa League semi-finals.
As expected, Real Madrid striker Karim Benzema is not in the squad after being snubbed since being involved in a sex tape-blackmail scandal in 2015.
The 29-year-old Nzonzi has just two caps.
Midfielders: Paul Pogba (Manchester United), Corentin Tolisso (Bayern Munich), Blaise Matuidi (Juventus), N'Golo Kante (Chelsea), Steven N'Zonzi (Sevilla). I put the group on top of everything and from there, I make choices that in my opinion are for the good of the France team.
Les Bleus were drawn alongside Australia, Denmark and Peru in Group C, and are the heavy favourites to advance to the knockout stages.
Before heading to Russian Federation, they will play three home friendlies, starting against the Republic of Ireland at the Stade de France on May 28.
Man shoots ex-wife's 3 children, her boyfriend dead
The children were identified as 4-year-old Drake Painter, 6-year-old Caydence Painter and 8-year-old Odin Painter. While Simpson's physical wounds will heal, she will be forever haunted by the deaths of her children.
Yanny or Laurel? Dori weighs in
We're not sure, but it's another good illustration that what we experience is subjective, with often no "right or wrong" answer. Play the clip (below) and listen for yourself! "Again, yelling does not make more of you".
Igor Kokoskov: Luka Doncic would 'fit great' on Suns
These are good days for the Suns, who have gone through three terrible seasons and eight consecutive playoff-less campaigns. The power forward averaged 10.9 points per game and 5.8 rebounds per contest while averaging only 21.8 minutes per game.
LG G7 ThinQ release date confirmed as May 31
Under the hood, the phone will be powered by Snapdragon 845 chipset coupled with 6GB of RAM and 128GB of internal storage. LG claimed it will compensate users 100 million won in case personal data is leaked from the used handsets .
Nintendo at E3 2018
Nintendo announced on Wednesday fans will need to reserve play slots to play Super Smash Bros. for Switch before June's show. Nintendo will also give out exclusive Nintendo Switch pins to random fans who bring their console with them to the show.
Rapper Mac Miller Arrested For DUI, Hit And Run
When cops arrived at the crash site, they were able to run Miller's plates and find out the address listed on his registration. Miller, whose real name is Malcolm James McCormick, was arrested for DUI at his home an hour later.