Daily aspirin to prevent heart attacks no longer recommended for older adults
Nigeria's HIV Prevalence Drops to Under 2%
Diabetes, hypertension key risk factors for kidney disease
New data in eternal debate over eggs, heart health
Outcry over Trump's cuts to Medicare hospital payments
Spravato Nasal Spray Approved for Depression
12 March 2019, 05:52 | Randall Craig
Ketamine is a medicinal and veterinary anaesthetic Credit Bob London Alamy Stock
The drug's active ingredient is s ketamine a derivative of ketamine. The nasal spray will carry the FDA's most stringent safety warning. Here & Now's Jeremy Hobson speaks with Dennis Charney, dean of the Icahn School of Medicine at Mount Sinai in NY. "It really has opened up a whole new way of thinking about depression", Gerard Sanacora, professor of psychiatry at Yale University School of Medicine and director of the Yale Depression Research Program, said of ketamine.
Spravato is a chemical mirror image of anesthetic ketamine, which is abused as a recreational party drug that goes by the street name Special K.
Nevertheless, many hope that this new treatment will be a step in the right direction for mental health in the United States. Patients who have treatment-resistant depression reported "rapid and sustained improvement" of symptoms.
Esketamine, developed by Johnson & Johnson, will be administered as a nasal spray and be used in conjunction with an oral antidepressant. Spravato is meant to treat patients who have major depressive disorder (MDD) and have not responded "adequately" to two at least two different types of antidepressants.
But esketamine presents some challenges because of its similarities to ketamine. By the second month, a patient will receive treatment once a week or every two weeks, which will reduce the cost to between US$2,3000 and US$3,500 per month.
Data so far indicates that esketamine is safe to use, "but it has to be used in a very well-regulated way to prevent issues related to addiction/substance use", Dr. Hwang says. The medication will not be dispensed directly to patients for home use. "It will only be available in approved and certified treatment centers". In a long-term study, patients in stable remission taking the medication who continued treatment with the medicine were 51% less likely to relapse versus those who maintained a regimen of a placebo and an oral antidepressant. The spray has been approved as an alternative for people resistant to other types of treatments.
Esketamine seems to help alleviate depression by acting on the NMDA/glutamate receptor, which is different from more recently popular antidepressants.
Johnson & Johnson said the wholesale cost of each treatment with ketamine will range from $590 to $885, depending on the dose.
Nick Foles is signing with Jaguars
Foles was again called to replace the injured Wentz for the final five games of the 2018 season, winning four of them. Foles was drafted by the Eagles in the third round of the 2012 draft after three years as the starter at Arizona.
WR Danny Amendola Has Made His Free Agency Decision
After four seasons with the New England Patriots , Trey Flowers is on to the next chapter of his National Football League career. The veteran wideout is in Detroit Monday taking a physical and as long as there are no complications, he will be a Lion.
TE Allen signing with Dolphins after Pats release
He was targeted only 26 times as a receiver in his two years in New England and caught 13 of those targets for 113 yards. The former Patriots tight end played behind Rob Gronkowski and was used in running situations for the most part.
Plane Believed to be Carrying Bouteflika Lands in Algeria
The president's plane touched down in the midst of a general strike, with numerous shops in the capital and other cities closed. An Algerian government plane, hidden from view in a hangar, was reported to have left Geneva around 1500 GMT.
Pregnant Meghan ditched her engagement ring today
While, we would never take the sparkler off, there may actually be a very practical reason why the duchess was spotted without it. Kate, on the other hand, opted for a bold look with a red coat dress by Catherine Walker paired with a matching red fascinator.