March 19, 2019

Eye scan may detect early signs of Alzheimer's

14 March 2019, 08:11 | Randall Craig

The Eyes Could Be The Window To Alzheimer's Disease, New Study Finds

Eye check-up to detect Alzheimer's disease

The study involved 39 people with Alzheimer's disease and 133 participants in a control group. The differences in density were statistically significant after researchers controlled for factors like age, gender, and level of education.

"While a wide range of other proposed blood tests for Alzheimer's disease are being developed, this is the first study to use a machine learning approach to identify sets of proteins in blood that are predictive of a biomarker in spinal fluid", notes the researcher for IBM's genomics research team. That appearance signifies a healthy brain, but in cases of Alzheimer's disease, the blood vessels appear different. In addition, a specific layer of the retina was thinner in those with Alzheimer's. An OCTA scan can even reveal changes in tiny capillaries - most less than half the width of a human hair - before blood vessel changes show up on a brain scan such as an MRI or cerebral angiogram, which highlight only larger blood vessels.

The findings were reported in Ophthalmology Retina, a publication of the American Academy of Ophthalmology.

A new kind of precise and non-invasive imaging called optical coherence tomography angiography (OCTA) has assisted much of the recent research on the eye's connection with Alzheimer's.

Dr Fekrat said: 'Our work is not done.

Early diagnosis will allow researchers to administer them sooner in the disease process which may lead to better results.

Alzheimer's remains an incurable, fatal disease suffered by millions of people from around the world, and can only be treated by palliative means.

With almost a large portion of the world living with Alzheimer's disease and no viable treatments or non-invasive tools for early diagnosis, the burden on the families and the economy becomes heavy.

Citing a previous research, Goudey said: "Examining the concentration of the peptide in an individual's spinal fluid provides an indication of risk decades before any memory related issues occur".

It would also give patients time to plan for the future with their families - while they still have their faculties, said the USA team.

Dr Fekrat said: "Early diagnosis of Alzheimer's disease is a huge unmet need". But such techniques to study the brain are invasive and costly.

In the US alone, 5.8 million people are living with Alzheimer's dementia, according to 2019 data from the Alzheimer's Association.

Other News

Trending Now

Man who missed Ethiopian flight: 'Too young to die'
It comes after the second fatal accident involving the 737 Max 8 model in less than five months. They were joined Wednesday by New Zealand, Thailand, and Vietnam.

NASA's new rocket won't be ready for moon shot next year
We have the first all-female spacewalk happening this month at the end of March, which is of course, National Women's Month. This first mission coming up - essentially a three-week test flight - would carry no crew and would not land.

Can't update status? Facebook and Instagram are down
Facebook is now down with people all around the globe having difficulty accessing the world's largest social network. Facebook seems to be down in various forms particularly for those who are trying to log in on desktop.

U.S.'s Bolton says Pakistan committed to easing tensions with India
Qureshi said that Pakistan Prime Minister Imran Khan made a decision to hand over the Indian Air Force pilot as a gesture of goodwill towards India.

Celebrations and Calls for Reform as the World Wide Web Turns 30
Berners-Lee has already outlined the solution to these problems a year ago, when he launched his Contract for the Web initiative. He also could not foresee the proliferation of hacking, criminal behaviour and hatred now spread online.

Millions left without electricity in Venezuela
But decades of underinvestment have damaged the major dams, and sporadic blackouts are commonplace. Critics say they have been getting worse since the nationalisation of the power grid in 2007.

PLAYERS: Tiger Woods talks about neck injury
Yes, the top 50 in the world are there, but the remainder of the field are decided by the FedExCup rankings on the PGA Tour. Last but certainly not least, I will end the article the ever popular sample lineup we like to do here at FantasyCPR .

Airlines canceling flights out of Denver on Wednesday ahead of expected blizzard
It already left more than 100,000 customers without power in Colorado as of Wednesday afternoon, according to Xcel Energy. The storm could also cause flooding, as rain falls on accumulated snow and rivers clogged with ice begin to rise.

Samsung Galaxy S10E review: smaller, cheaper, better
Samsung is apparently working on a budget flagship that's going to be priced lower than the Galaxy S10e . Samsung claims the "e" stands for "essentials", but there's a lot more to this phone than just that.

YouTube Music launches in SA, but how does the price compare?
You can track downs songs using descriptions, lyrics or emojis with the Smart Search which is available in Zulu and Xhosa. India's music streaming market is attracting global giants and YouTube is the latest to enter the competitive sector.