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profishingrods.com March 19, 2019


Eye scan may detect early signs of Alzheimer's

14 March 2019, 08:11 | Randall Craig

The Eyes Could Be The Window To Alzheimer's Disease, New Study Finds

Eye check-up to detect Alzheimer's disease

The study involved 39 people with Alzheimer's disease and 133 participants in a control group. The differences in density were statistically significant after researchers controlled for factors like age, gender, and level of education.

"While a wide range of other proposed blood tests for Alzheimer's disease are being developed, this is the first study to use a machine learning approach to identify sets of proteins in blood that are predictive of a biomarker in spinal fluid", notes the researcher for IBM's genomics research team. That appearance signifies a healthy brain, but in cases of Alzheimer's disease, the blood vessels appear different. In addition, a specific layer of the retina was thinner in those with Alzheimer's. An OCTA scan can even reveal changes in tiny capillaries - most less than half the width of a human hair - before blood vessel changes show up on a brain scan such as an MRI or cerebral angiogram, which highlight only larger blood vessels.

The findings were reported in Ophthalmology Retina, a publication of the American Academy of Ophthalmology.

A new kind of precise and non-invasive imaging called optical coherence tomography angiography (OCTA) has assisted much of the recent research on the eye's connection with Alzheimer's.

Dr Fekrat said: 'Our work is not done.

Early diagnosis will allow researchers to administer them sooner in the disease process which may lead to better results.




Alzheimer's remains an incurable, fatal disease suffered by millions of people from around the world, and can only be treated by palliative means.

With almost a large portion of the world living with Alzheimer's disease and no viable treatments or non-invasive tools for early diagnosis, the burden on the families and the economy becomes heavy.

Citing a previous research, Goudey said: "Examining the concentration of the peptide in an individual's spinal fluid provides an indication of risk decades before any memory related issues occur".

It would also give patients time to plan for the future with their families - while they still have their faculties, said the USA team.

Dr Fekrat said: "Early diagnosis of Alzheimer's disease is a huge unmet need". But such techniques to study the brain are invasive and costly.

In the US alone, 5.8 million people are living with Alzheimer's dementia, according to 2019 data from the Alzheimer's Association.



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